Recent developments with muscle relaxants and their antagonists
نویسندگان
چکیده
منابع مشابه
– Pharmacology of Muscle Relaxants and Their Antagonists
In 1942 Griffith and Johnson suggested that d-tubocurarine (dTc) is a safe drug to use during surgery to provide skeletal muscle relaxation. One year later, Cullen described its use in 131 patients who had received general anesthesia for their surgery. In 1954, Beecher and Todd reported a sixfold increase in mortality in patients receiving dTc versus those who had not received a relaxant. The i...
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Anesthesiologists perceive that the ideal muscle relaxant is not yet available, particularly the nondepolarizing one with a rapid onset and a short duration of action. There is also a need for relaxants with different durations of action but which would be free from side effects. During the process of this development several new compounds have been tested and four have reached an advanced stat...
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Quinolones are a very important family of antibacterial agents that are widely prescribed for the treatment of infections in humans. Since their discovery in the early 1960s, the quinolone group of antibacterials has generated considerable clinical and scientific interest. Two major groups of compounds have been developed from the basic molecule: quinolones and naphthyridones. The 4-pyridone-3-...
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ژورنال
عنوان ژورنال: Canadian Anaesthetists’ Society Journal
سال: 1979
ISSN: 0008-2856,1496-8975
DOI: 10.1007/bf03013775